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As we age, lose weight, or go through rapid weight loss, we don’t just lose overall volume. We can lose the natural, plump fatty tissue that gives our face its shape and support. Traditional fillers simply add volume to an area. Lipoderma® by Britecyte takes a different approach. It uses donated human adipose tissue to restore lost fatty tissue.
At Tannan Plastic Surgery, board-certified plastic surgeon Dr. Shruti Tannan offers Lipoderma as an option for patients dealing with facial volume loss, including changes that come with aging or significant weight loss.
Lipoderma is a natural filler made from donated human fat (adipose) tissue. Unlike traditional dermal fillers, which are made from synthetic materials, Lipoderma is made from real fat tissue that has been carefully processed to make it safe to use. The manufacturer’s technology removes genetic material from the donated tissue while keeping its natural structure intact.
Lipoderma is made of two things:
It’s about 90% fat cells and 10% supportive framework. This “like-for-like” approach is what sets Lipoderma apart from a regular synthetic filler. Instead of adding a foreign material, it works with your body, replacing lost fatty tissue with real, donated fatty tissue that helps you rebuild naturally.
Fat does more than add volume. The layer of fat beneath your skin helps shape your face, gives it support, and creates smooth transitions between different facial features. With aging, certain medications, and weight loss, this layer can thin out.
When that happens, you may notice:
A conventional filler can add volume, but Lipoderma is designed to restore the fat layer itself.
Losing a significant amount of weight can change the face, no matter how the weight comes off. But patients taking GLP-1 medications often notice facial changes fairly quickly, since the weight tends to come off fast.
As body fat decreases, some patients develop:
This is sometimes called “GLP-1 face” or “Ozempic face.” It’s not that these medications damage the skin. It’s that losing a lot of weight quickly reduces the fat that normally supports your skin and facial structure.
Lipoderma is designed to restore that lost fat volume using donated fat tissue. If you’re still actively losing weight, Dr. Tannan may recommend waiting until your weight has stabilized before doing facial volume restoration, so you get the best possible result.
The simplest way to think about it: traditional filler adds material, while Lipoderma restores fat tissue. Traditional fillers are manufactured substances designed to add volume, and they vary in makeup, how they behave, and how long they last. Lipoderma, on the other hand, is human fat tissue that comes from a donor.
| Traditional Dermal Filler | Lipoderma |
|---|---|
| Manufactured/synthetic injectable material | Human adipose tissue allograft |
| Adds volume | Restores lost adipose tissue |
| Composition depends on filler | Native adipose tissue architecture |
| No donor tissue required | Donor-derived human tissue |
| Typically gradually resorbs depending on product | Designed to integrate and remodel over time |
| Primarily a volume-based approach | Structural fat restoration |
The right choice depends on the problem being treated. Dr. Tannan may recommend a traditional filler, Lipoderma, your own fat (fat grafting), or surgery, depending on your anatomy and goals.
Traditional fat grafting uses your own fat. Fat is taken from another area of your body, processed, and then transferred to the area that needs volume. This remains a great option for patients who have enough donor fat and are open to a surgical procedure.
Lipoderma offers another path. It’s an off-the-shelf, donor-derived tissue, so there’s no need for liposuction or a donor site on your own body.
This can be especially helpful for patients who:
Lipoderma doesn’t replace fat grafting for everyone. It simply gives us another tool to work with.
Lipoderma is designed for restoring volume in specific areas. At Tannan Plastic Surgery, areas we may consider include:
Losing cheek fat can flatten the midface and create a hollow look. Restoring volume here can help recreate a smoother transition between the lower eyelid and cheek.
Losing fat here can contribute to hollows beneath the eyes. Because the anatomy around the eyes is delicate, this area requires careful evaluation to determine whether and where volume restoration makes sense.
Losing volume in the temples can create a more angular look in the upper face. Some patients benefit from restoring this lost volume.
With age or weight loss, the backs of the hands can lose their protective layer of fat, making veins, tendons, and bones more visible. Lipoderma may help restore volume here in the right candidates.
Your treatment starts with a consultation with Dr. Shruti Tannan, a board-certified plastic surgeon in Raleigh, or her nurse injector, who works closely with Dr. Tannan.
During your consultation, Dr. Tannan will look at:
From there, she’ll determine whether Lipoderma is right for you and build a treatment plan around your needs. Lipoderma is typically placed just beneath the skin using a small cannula. The treatment is done in-office with local anesthesia as needed. The exact approach depends on the area being treated and how much volume is needed.
Lipoderma adds volume right away, so you’ll likely see improvement immediately after your treatment. That said, this initial look isn’t the final result. Swelling and bruising can temporarily change the appearance of the treated area, and the tissue will continue to settle and integrate as you heal.
In the weeks and months after treatment, you may experience:
Most patients have relatively little downtime, though recovery can vary depending on the area treated and your individual healing. Dr. Tannan will give you specific aftercare instructions after your procedure.
Unlike traditional fillers, Lipoderma isn’t meant to just provide temporary volume. You’ll see an immediate improvement, and the tissue continues to integrate and settle over time. Current clinical data shows results lasting at least six months, and longer-term results are still being studied. Because Lipoderma is a newer technology, we can’t promise a specific number of years of correction.
Your results will depend on things like:
If you need more volume down the road, Dr. Tannan can help determine if another treatment makes sense.
Lipoderma is designed to integrate into your tissue and remodel over time. It’s donor-derived allograft, not fat harvested from your own body, so your body goes through a natural remodeling process as it incorporates the tissue, and your final result develops gradually. This is why we encourage patients to think of Lipoderma as restoring tissue, rather than just another injectable filler.
You may hear Lipoderma fat-based filler described in “regenerative” terms, since it contains natural adipose tissue and a supportive framework, and is designed to integrate and remodel in the body. We prefer to describe it more simply: Lipoderma is donated human fat tissue, processed to remove markers that could trigger an immune reaction while keeping its natural structure, and designed to restore lost soft-tissue volume.
Lipoderma comes from screened human donors and is processed through an established tissue-banking system, following applicable tissue-bank and FDA requirements.
As with any procedure involving human tissue, there are potential risks to be aware of. During your consultation, we’ll walk you through the risks, benefits, limitations, and alternatives to treatment. Being derived from human tissue doesn’t mean a product is risk-free. Careful patient selection, a sterile procedure, proper placement, and good follow-up care all remain essential.
You may be a good candidate if you have localized volume loss and want a more natural contour, without going through liposuction or a bigger surgical procedure.
Lipoderma may especially appeal to patients who have experienced:
The best candidates understand that the goal is restoration, not transformation.
There’s no single treatment that works for every type of facial aging or volume loss. Sometimes the right answer is a traditional filler. Sometimes it’s Lipoderma. Sometimes it’s your own fat. And sometimes surgery is the most appropriate option.
Dr. Tannan takes an individualized approach based on your anatomy, rather than simply adding volume wherever a hollow appears. The goal isn’t to make you look different.
The goal is to restore the structure that made you look like you.
If you’ve noticed facial hollowing or volume loss from weight loss, GLP-1 treatment, or simply the passage of time, Lipoderma fat-based filler may offer a new way to restore lost fat tissue.
Schedule a consultation with Dr. Shruti Tannan at Tannan Plastic Surgery in Raleigh to find out if Lipoderma is right for you.
Call Tannan Plastic Surgery at (919) 797-0996 to schedule your consultation.
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